Explore 375 cruise vacations

Showing 24 cruise vacations: North America, April 2026 - April 2027

Showing 11 cruise vacations that match your search

Panama Canal & Pacific Wonders

Miami, Florida • Cartagena, Colombia • Colón, Panama • Panama Canal (Cruising), Panama • Puntarenas, Costa Rica • Puerto Quetzal, Guatemala • Cabo San Lucas • Los Angeles, California

Insider cabins from

$6,688 ~~$9,912~~

per Cabin

16 nights

Brilliant Lady

Brilliant Lady's Inaugural Season

BOOK NOW

+ instant savings applied*

SAIL INTO DEEPER SAVINGS: 75% Off 2nd Sailor

Insider cabins from

$6,688 ~~$9,912~~

per Cabin

Departing on:

2026

Sat, Mar 21 - Mon, Apr 06

from (US$)$6,688

Brilliant Lady LA MerMaiden

Los Angeles, California • Santa Barbara, California • San Diego, California • Ensenada • Los Angeles, California

Insider cabins from

$1,790 ~~$2,600~~

per Cabin

5 nights

Brilliant Lady

Brilliant Lady's Inaugural Season

BOOK NOW

+ instant savings applied*

SAIL INTO DEEPER SAVINGS: 75% Off 2nd Sailor

Insider cabins from

$1,790 ~~$2,600~~

per Cabin

Departing on:

2026

Tue, Apr 07 - Sun, Apr 12

from (US$)$1,790

California (and Mexico) Dreamin'

Los Angeles, California • Cabo San Lucas • Mazatlàn • Los Angeles, California

Sea View cabins from

$2,508 ~~$3,760~~

per Cabin

6 nights

Brilliant Lady

Brilliant Lady's Inaugural Season

BOOK NOW

+ instant savings applied*

SAIL INTO DEEPER SAVINGS: 75% Off 2nd Sailor

Sea View cabins from

$2,508 ~~$3,760~~

per Cabin

Departing on:

2026

Sun, Apr 12 - Sat, Apr 18

from (US$)$2,508

Hollywood Sunsets & Mexican Horizons

Los Angeles, California • Cabo San Lucas • Mazatlàn • Puerto Vallarta • Los Angeles, California

Insider cabins from

$2,088 ~~$3,044~~

per Cabin

7 nights

Brilliant Lady

Brilliant Lady's Inaugural Season

BOOK NOW

+ instant savings applied*

SAIL INTO DEEPER SAVINGS: 75% Off 2nd Sailor

Insider cabins from

$2,088 ~~$3,044~~

per Cabin

Departing on:

2026Best Rate

Sat, Sep 19 - Sat, Sep 26

from (US$)$2,088

2026

Sun, Apr 26 - Sun, May 03

from (US$)$3,290

2026

Sat, Sep 26 - Sat, Oct 03

from (US$)$2,088

LA Lights & Vancouver Vistas

Los Angeles, California • Catalina Island, California • San Francisco, California • Astoria, Oregon • Victoria, British Columbia • Vancouver, British Columbia

Insider cabins from

$2,384 ~~$3,488~~

per Cabin

8 nights

Brilliant Lady

Brilliant Lady's Inaugural Season

BOOK NOW

+ instant savings applied*

SAIL INTO DEEPER SAVINGS: 75% Off 2nd Sailor

Insider cabins from

$2,384 ~~$3,488~~

per Cabin

Departing on:

2026

Sun, May 03 - Mon, May 11

from (US$)$2,384

Vancouver Down the Cali Coast

Vancouver, British Columbia • Astoria, Oregon • San Francisco, California • Santa Barbara, California • Catalina Island, California • San Diego, California • Los Angeles, California

Insider cabins from

$2,386 ~~$3,474~~

per Cabin

8 nights

Brilliant Lady

BOOK NOW

+ instant savings applied*

SAIL INTO DEEPER SAVINGS: 75% Off 2nd Sailor

Insider cabins from

$2,386 ~~$3,474~~

per Cabin

Departing on:

2026

Fri, Sep 11 - Sat, Sep 19

from (US$)$2,386

Picturesque Panama Canal Collective

Los Angeles, California • Cabo San Lucas • Puerto Quetzal, Guatemala • Puntarenas, Costa Rica • Panama City, Panama • Panama Canal (Cruising), Panama • Cartagena, Colombia • Miami, Florida

Insider cabins from

$6,292 ~~$9,136~~

per Cabin

17 nights

Brilliant Lady

BOOK NOW

+ instant savings applied*

SAIL INTO DEEPER SAVINGS: 75% Off 2nd Sailor

Insider cabins from

$6,292 ~~$9,136~~

per Cabin

Departing on: