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🎉 instant savings applied*

Panama Canal & Pacific Wonders

16-night voyage on Brilliant Lady
One way from Miami, Florida, USA
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🎉 instant savings applied*

Coastal culture in Cartagena

This iconic one-way voyage from Miami to Los Angeles visits Cartagena, Colon, Puntarenas, Puerto Quetzal, and Cabo San Lucas, with an awe-inspiring trip through the Panama Canal on the way. After you make your way through the famed canal, enjoy the pristine white sand beaches of Cabo San Lucas, a tropical paradise you’ll remember long after you’ve disembarked.
Map of Panama Canal & Pacific Wonders itinerary

Panama Canal & Pacific Wonders • 16 Nights
Sailing on Brilliant Lady
  • Day
    PORT
  • 1
    ItineraryListIcon-img
    Miami, Florida, USA
    Departs at 05:00 PM, local time
    📣 All aboard 2 hrs before departure
  • 2
    ItineraryListIcon-img
    Sailing
  • 3
    ItineraryListIcon-img
    Sailing
  • 4
    ItineraryListIcon-img
    Cartagena, Colombia
    09:00 AM - 05:00 PM, local time
  • 5
    ItineraryListIcon-img
    Colón, Panama
    11:00 AM - 08:00 PM, local time
  • 6
    ItineraryListIcon-img
    Panama Canal (Cruising), Panama
  • 7
    ItineraryListIcon-img
    Sailing
  • 8
    ItineraryListIcon-img
    Puntarenas, Costa Rica
    08:00 AM - 06:00 PM, local time
  • 9
    ItineraryListIcon-img
    Sailing
  • 10
    ItineraryListIcon-img
    Puerto Quetzal, Guatemala
    08:00 AM - 08:00 PM, local time
  • 11
    ItineraryListIcon-img
    Sailing
  • 12
    ItineraryListIcon-img
    Sailing
  • 13
    ItineraryListIcon-img
    Sailing
  • 14
    ItineraryListIcon-img
    Cabo San Lucas, Mexico
    08:00 AM - 05:00 PM, local time
  • 15
    ItineraryListIcon-img
    Sailing
  • 16
    ItineraryListIcon-img
    Sailing
  • 17
    ItineraryListIcon-img
    Los Angeles, California, USA
    Arrives at 06:30 AM, local time

The Virgin Voyages Experience

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Terminal V at PortMiami

Uniting the energy of Miami with nautical nods to the history of sailing, we’re infusing our own terminal with the same incredible ethos as our ships.

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Hassle-free embarkation

Pre-upload your travel docs to the Virgin Voyages app, get Ready to Sail before leaving home, and make boarding a (sea)breeze in just a few minutes.

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Keeping it local

We’ve teamed up with locals in each of our ports to reveal sides of places you’ve yet to explore — from the people who know the destinations best.

Cartagena, Colombia

Coastal culture in Cartagena
Experience one of Colombia’s most breezy and colorful cities, exploring the 16th-century Old Town, with cobblestone streets and colonial buildings, and pristine coastal beaches. Whether you’re wandering the Plaza de Bolivar, marveling at San Felipe de Barajas Fort, or kicking back on the white sands of nearby Isla de Barú, there’s so much to do in Cartagena you’ll wish you could spend several weeks here.
Select your voyage dates
Select your voyage dates
1 Sailings between May 2025 - August 2026
🎉 Brilliant Lady's Inaugural Season
March 2026
🎉Sat, Mar 21 - Mon, Apr 06Brilliant Lady's Inaugural Season
from $6,688
75% Off 2nd Sailor
Brilliant Lady's Inaugural Season
Average price per cabin based on 2 Sailors in a cabin (Incl. taxes & fees)

Rest your head

Coffee (or cocktails) in your terrace hammock overlooking the waves, or waking up late in your own cocoon, here are the cabins you can choose from...
Always Included Luxury
Over $1000 in value. The luxury you deserve — without the nickel & diming from the others. Look (far) beyond the headline rate.

WiFi

Browse, post, and stay connected on board.

Tips & Gratuities

We take care of our Crew. You just enjoy.

All Dining

20+ eateries with Michelin-star chef curated menus.

Soda & Water

Non-pressed juices, teas, and drip coffee, too!

Fitness Classes

Yoga, meditation, cycling, HIIT classes, and more!

Entertainment

Jaw-dropping shows? Always included.

Cartagena, Colombia

Coastal culture in Cartagena
Experience one of Colombia’s most breezy and colorful cities, exploring the 16th-century Old Town, with cobblestone streets and colonial buildings, and pristine coastal beaches. Whether you’re wandering the Plaza de Bolivar, marveling at San Felipe de Barajas Fort, or kicking back on the white sands of nearby Isla de Barú, there’s so much to do in Cartagena you’ll wish you could spend several weeks here.

Have someone you think would ❤️ this voyage?

$6,688 $9,912
avg. starting price per cabin
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or from $/month.